Uracyst® (Sterile Sodium Chondroitin Sulfate Solution 2%) available in 20 mL vials is an effective GAG replenishment therapy. Chondroitin Sulfate is an acidic mucopolysaccharide and is one of the most prevalent bladder GAG components. There have been numerous studies showing that GAG replenishment therapies are effective in treating GAG deficient Interstitial Cystitis patients. It is felt they help to re-establish bladder GAG barrier function.

Uracyst® is instilled into the bladder in Interstitial Cystitis patients weekly for 4-6 weeks, then monthly thereafter until symptoms are resolved. Uracyst® should be held in the bladder for a minimum of 30 minutes. Response will vary from patient to patient but optimum response usually takes 4 to 6 months and should be continued for at least one (1) year before interrupting treatment (see published research pg 11). When a patient experiences flareups while on monthly therapy, they should revert to weekly therapy until such time that the symptoms have subsided, then go back to monthly treatments. For some patients with severe Interstitial Cystitis, a more aggressive therapy is recommended. These patients should have instillations on a bi-weekly basis for 6 weeks. Instillations are then continued on a monthly basis for twelve (12) months.