
GAG Layer Physiology

Research has shown that over 70% of Interstitial Cystitis patients have defects in the protective lining on the wall of the urinary bladder. This lining is made up of substances called mucins or Glycosaminoglycans (GAGs), which protect the bladder wall from toxic effects of urine and its contents. Damage causes leaks in the protective GAG layer, which may then allow substances in urine to pass into the bladder wall and trigger Interstitial Cystitis symptoms. Products used for bladder instillations are:
Non GAG replenishment
GAG Replenishment
Dietary Suggestions For Interstitial Cystitis
Food Category |
Permitted Foods |
Foods to Avoid or Use Cautiously |
Fruits |
Blueberries, melons other than cantaloupes, and pears |
All other fruits and juices made from them |
Vegetables |
Potatoes, homegrown tomatoes, beets, cabbage, cucumber, celery, carrot, zucchini, turnip, squash, parsnip, plantain, broccoli, cauliflower, brussels sprouts, bok choy, watercress and vegetables other than those listed on the right |
Fava beans, lima beans onions, rhubarb, tofu and store-bought tomatoes |
Milk/Dairy |
White chocolate, cottage cheese, American cheese, milk |
Aged cheeses, sour cream, eggs, yogurt, chocolate |
Carbohydrates/Grains |
Pasta, rice, and breads other than those listed on the right |
Rye and sourdough breads |
Meats/Fish |
Poultry, fresh fish, and meats other than those listed on the right |
Aged, canned, cured, processed, and smoked meats and fish; anchovies; caviar; chicken livers; corned beef; and meats that contain nitrates or nitrites |
Nuts |
Almonds, cashews, and pine nuts |
Most other nuts |
Beverages |
Bottled or spring water; decaffeinated, acid-free coffee and tea; carrot juice, celery juice and some herbal teas |
Alcoholic beverages; beer and wine; carbonated drinks; coffee, tea, and cranberry juice |
Seasonings |
Garlic and seasonings other than those listed on the right |
Mayonnaise, miso, spicy foods (especially Chinese, Mexican, Indian, and Thai foods) |
Preservatives |
Benzyl alcohol, citric acid, monosodium glutamate, aspartame, saccharin, and foods containing preservatives, artificial ingredients/colors |